|Place of Origin:||China|
|Minimum Order Quantity:||Negotiable|
|Packaging Details:||1kg Sterile aluminum foil bag or discreet and tight safe packing for Customs pass guaranteed|
|Delivery Time:||Within 24h after payment|
|Payment Terms:||, MoneyGram, T/T, Bit-coin|
|Supply Ability:||Mass stock|
|Product Name:||SR9011||Appreance:||White Powder|
|Molecular Weight:||C23H31ClN4O3S||Function:||Muscle Building|
|Appearance||White crystalline powder|
|Packing||1kg net/foil bag, 5kg/drum.|
|Storage||Shading , Confined Preservation|
|Usage||For obesity, diabetes, dyslipidemia and cardiovascular disease|
SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates. SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols. Usage levels of 5% to 10% by weight are recommended.SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB- with an EC50 ~790 nM and REV-ERB-with EC50 ~560 nM.
It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB- and REV-ERB- play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure.
Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.
SARMS series of products
|CAS: 401900-40-1||Andarine (S4)|
|Best Quality||Professional leading manufacturers in China. Strict quality control before products are allowed to sell.|
|Competitive Price||Factory direct sales. Best prices you're sure to be satisfied.|
|Safe Packing||Professional packing department which have more than 16 years experience in disguising packages|
|Fast Delivery||Plenty in stock, delivery within 24 hours after the payment. Fast and secure delivery by DHL, TNT, FedEx, HKEMS, UPS, etc.|
|Payment||T/T, , Money Gram, Bitcoin.|
|Service||Photos of parcel and tracking number offered timely; 24/7 online helpful service|
|Discount||Specials are possible when client's order is big enough, including the discount policy|